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dc.contributor.authorBurrow, Keeganen
dc.contributor.authorYoung, W.en
dc.contributor.authorHammer, N.en
dc.contributor.authorSafavi, S.en
dc.contributor.authorScholze, M.en
dc.contributor.authorMcConnell, M.en
dc.contributor.authorBarr, D.en
dc.contributor.authorReid, M.en
dc.contributor.authorBekhit, Alaa E. A.en
dc.date.accessioned2020-09-16T01:57:17Z
dc.date.available2020-08-07en
dc.date.issued2020-08en
dc.identifier.issn2304-8158en
dc.identifier.urihttps://hdl.handle.net/10182/12676
dc.description.abstractThis study assessed the effect of cow milk (CM) and sheep milk (SM) consumption on the micro-structure, mechanical function, and mineral composition of rat femora in a male weanling rat model. Male weanling rats were fed a basal diet with a 50% reduction in calcium and phosphorus content (low Ca/P-diet) supplemented with either SM or CM. Rats were fed for 28 days, after which the femora were harvested and stored. The femora were analyzed by μ-CT, three-point bending, and inductively coupled plasma–mass spectrometry (ICP-MS). The addition of either milk to the low Ca/P-diet significantly increased (p < 0.05) trabecular bone volume, trabecular bone surface density, trabecular number, cortical bone volume, and maximum force, when compared to rats that consumed only the low Ca/P-diet. The consumption of either milk resulted in a significant decrease (p < 0.05) in trabecular pattern factor, and cortical bone surface to volume ratio when compared to rats that consumed only the low Ca/P-diet. The results were achieved with a lower consumption of SM compared to that of CM (p < 0.05). This work indicates that SM and CM can help overcome the effects on bone of a restriction in calcium and phosphorus intake.en
dc.format.extent14en
dc.language.isoenen
dc.publisherMDPIen
dc.relationThe original publication is available from - MDPI - https://doi.org/10.3390/foods9081070 - https://doi.org/10.3390/foods9081070en
dc.relation.urihttps://doi.org/10.3390/foods9081070en
dc.rights© 2020 by the authors. Licensee MDPI, Basel, Switzerlanden
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectboneen
dc.subjectdeficient dieten
dc.subjectdairyen
dc.subjectmineralsen
dc.subjectmicro-computed tomographyen
dc.subjectinductively coupled plasma–mass spectrometryen
dc.subjectmechanical propertiesen
dc.subjectsheepen
dc.subjectcowen
dc.subjectinductively coupled plasma-mass spectrometryen
dc.titleThe effect of the supplementation of a diet low in calcium and phosphorus with either sheep milk or cow milk on the physical and mechanical characteristics of bone using a rat modelen
dc.typeJournal Article
lu.contributor.unitLincoln Universityen
lu.contributor.unitFaculty of Agriculture and Life Sciencesen
lu.contributor.unit/LU/Agriculture and Life Sciences/FOODen
lu.contributor.unitDepartment of Wine, Food and Molecular Biosciencesen
dc.identifier.doi10.3390/foods9081070en
dc.subject.anzsrc090801 Food Chemistry and Molecular Gastronomy (excl. Wine)en
dc.subject.anzsrc090802 Food Engineeringen
dc.subject.anzsrc0908 Food Sciencesen
dc.relation.isPartOfFoodsen
pubs.issue8en
pubs.notesDate of acceptance: 05 Aug 2020en
pubs.organisational-group/LU
pubs.organisational-group/LU/Agriculture and Life Sciences
pubs.organisational-group/LU/Agriculture and Life Sciences/FOOD
pubs.organisational-group/LU/Agriculture and Life Sciences/WFMB
pubs.publication-statusPublished onlineen
pubs.publisher-urlhttps://doi.org/10.3390/foods9081070en
pubs.volume9en
dc.rights.licenceAttributionen
lu.identifier.orcid0000-0002-5411-7832
pubs.article-number1070en


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