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dc.contributor.authorLejeune, A.en
dc.contributor.authorMonahan, F. J.en
dc.contributor.authorMoloney, A. P.en
dc.contributor.authorEarley, B.en
dc.contributor.authorBlack, Alistairen
dc.contributor.authorCampion, D. P.en
dc.contributor.authorEnglishby, T.en
dc.contributor.authorReilly, P.en
dc.contributor.authorO'Doherty, J.en
dc.contributor.authorSweeney, T.en
dc.date.accessioned2017-07-07T05:02:30Z
dc.date.available2010-03-31en
dc.date.issued2010en
dc.identifier.citationLejeune at al. (2010). Peripheral and gastrointestinal immune systems of healthy cattle raised outdoors at pasture or indoors on a concentrate-based ration. BMC Veterinary Research, 6, 19-28. doi:10.1186/1746-6148-6-19en
dc.identifier.issn1746-6148en
dc.identifier.urihttps://hdl.handle.net/10182/8281
dc.description.abstractBackground: Despite an increasing preference of consumers for beef produced from more extensive pasture-based production systems and potential human health benefits from the consumption of such beef, data regarding the health status of animals raised on pasture are limited. The objective of this study was to characterise specific aspects of the bovine peripheral and the gastrointestinal muscosal immune systems of cattle raised on an outdoor pasture system in comparison to animals raised on a conventional intensive indoor concentrate-based system. Results: A number of in vitro functional tests of immune cells suggested subtle differences between the animals on the outdoor versus indoor production systems. There was a decrease in the number of neutrophils and monocytes engaged in phagocytosis in outdoor cattle (P < 0.01 and P < 0.05, respectively) in comparison to those indoors. Following mitogen stimulation, a lower level of interferon-γ was produced in leukocytes from the outdoor animals (P < 0.05). There was evidence of a gastrointestinal nematode infection in the outdoor animals with elevated levels of serum pepsinogen (P < 0.001), a higher number of eosinophils (P < 0.05) and a higher level of interleukin-4 and stem cell factor mRNA expression (P < 0.05) in the outdoor animals in comparison to the indoor animals. Lower levels of copper and iodine were measured in the outdoor animals in comparison to indoor animals (P < 0.001). Conclusion: Despite distinctly contrasting production systems, only subtle differences were identified in the peripheral immune parameters measured between cattle raised at pasture in comparison to animals raised on a conventional intensive indoor concentrate-based production system.en
dc.format.extent19-28en
dc.language.isoenen
dc.publisherBioMed Central Ltden
dc.relationThe original publication is available from - BioMed Central Ltd - https://doi.org/10.1186/1746-6148-6-19 - http://www.biomedcentral.com/1746-6148/6/19en
dc.relation.urihttps://doi.org/10.1186/1746-6148-6-19en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectimmune systemsen
dc.subjectcattleen
dc.subjectraiseden
dc.subjectoutdoorsen
dc.subjectindoorsen
dc.subjectVeterinary Sciencesen
dc.titlePeripheral and gastrointestinal immune systems of healthy cattle raised outdoors at pasture or indoors on a concentrate-based rationen
dc.typeJournal Article
lu.contributor.unitLincoln Universityen
lu.contributor.unitFaculty of Agriculture and Life Sciencesen
lu.contributor.unitDepartment of Agricultural Sciencesen
lu.contributor.unitResearch Management Officeen
lu.contributor.unit/LU/Research Management Office/2018 PBRF Staff groupen
dc.identifier.doi10.1186/1746-6148-6-19en
dc.subject.anzsrc070202 Animal Growth and Developmenten
dc.subject.anzsrc0702 Animal Productionen
dc.subject.anzsrc0707 Veterinary Sciencesen
dc.subject.anzsrc0605 Microbiologyen
dc.subject.anzsrc0601 Biochemistry And Cell Biologyen
dc.relation.isPartOfBMC Veterinary Researchen
pubs.notesDate of acceptance: 31 Mar 2010en
pubs.organisational-group/LU
pubs.organisational-group/LU/Agriculture and Life Sciences
pubs.organisational-group/LU/Agriculture and Life Sciences/AGSC
pubs.organisational-group/LU/Research Management Office
pubs.organisational-group/LU/Research Management Office/2018 PBRF Staff group
pubs.publication-statusPublisheden
pubs.publisher-urlhttp://www.biomedcentral.com/1746-6148/6/19en
pubs.volume6en
dc.rights.licenceAttributionen


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