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Mathematical modelling of the core regulatory feedback mechanisms of p53 protein that decide cell fate
(Lincoln University, 2014)
Cells defence against stresses that can cause DNA damage (single-strand breaks, double-strand breaks) is crucial in safeguarding the integrity of the genome and the survival of the organism as a whole. One of the genes ...
An improved stochastic modelling framework for biological networks
(Modelling and Simulation Society of Australia and New Zealand, 2019-12)
It has become very clear that stochasticity in biology is a rule rather than exception. Gillespie stochastic simulation algorithm (GSSA) (direct method) is the first algorithm proposed to model stochasticity in biochemical ...