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Effects of T-2 toxin on Pacific white shrimp Litopenaeus vannamei: Growth, and antioxidant defenses and capacity and histopathology in the hepatopancreas
(Taylor & Francis on behalf of the American Fisheries Society, 2017)
© American Fisheries Society 2017. Modified–masked T-2 toxin (mT-2) formed during metabolism in edible aquatic animals may go undetected by traditional analytical methods, thereby underestimating T-2 toxicity. The effects ...
Effects of T-2 toxin on histopathology, fatty acid and water distribution of shrimp (Litopenaeus vannamei) muscle
(Taylor & Francis, 2019)
T-2 toxin (T-2), one of the naturally occurring mycotoxins, often accumulates in aquatic animals from contaminated feed. Shrimp (n = 30 per group) were fed with different concentrations (0, 0.5, 1.5, 4.5 and 13.5 mg kg⁻¹) ...
Biotransformation enzyme activities and phase I metabolites analysis in Litopenaeus vannamei following intramuscular administration of T-2 toxin
(Taylor & Francis Group, 2018)
T-2 toxin (T-2) is a type-A trichothecene produced by Fusarium that causes toxicity to animals. T-2 contamination of grain-based aquatic feed is a concern for the industries related to edible aquatic crustacean species ...
Effects of T‐2 toxin on the muscle proteins of shrimp (Litopenaeus vannamei) – a proteomics study
(Society of Chemical Industry, 2019-08-23)
BACKGROUND: T-2 toxin (T-2) is a potent mycotoxin and a common contaminant of aquatic animal feed, posing a serious risk to health and aquatic animals. We investigated the effect of T-2 on shrimp muscle proteins using ...
Effects of T-2 toxin on digestive enzyme activity, intestinal histopathology and growth in shrimp Litopenaeus vannamei
(Springer Nature, 2019-09-11)
T-2 toxin (T-2), a naturally occurring mycotoxin that often accumulates in aquatic animals via contaminated feed, is toxic to animals, including humans. In this study, six groups of shrimp (n = 30 shrimps/group) were given ...
Effect of T-2 toxin-injected shrimp muscle extracts on mouse macrophage cells (RAW264.7)
(Taylor & Francis, 2018)
Following intramuscular injections of 0.1 mL, 3 mg kg ⁻¹ BW ⁻¹ (1/10 LD₅₀) T-2 toxin (T-2), the tissue concentration of T-2 in shrimp was quantitatively detected using LC-MS/MS. The biological half-time (t½) of T-2 in blood ...
Preparation of T-2-glucoronide with rat hepatic microsomes and its use along with T-2 for activation of the JAK/STAT signaling pathway in RAW264.7 cells
(American Chemical Society, 2017-06-14)
T-2 toxin (T-2), one of the most toxic trichothecene A-type mycotoxins, is biotransformed in animal tissues to modified T-2s (mT-2s) including T-2 glucuronide (T-2-GlcA). In this study, the optimal conditions for T-2-GlcA ...
Selection and evaluation of indexes commonly used to determine contamination with T-2 toxin in Pacific white shrimp Litopenaeus vannamei by the grey relational method
(Wiley on behalf of the American Fisheries Society, 2017-09)
The objectives of the present study were to evaluate the effects of different concentrations of the mycotoxin T-2 toxin in feed on muscle performance in the Pacific white shrimp Litopenaeus vannamei, evaluate indexes of ...