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Identification of the ovine keratin-associated protein KAP1-2 gene (KRTAP1-2)
(John Wiley and Sons, 2011)
Abstract: Keratin-associated proteins (KAPs) are a major component of wool and other keratin-containing tissues. While four KAP1-n proteins have been identified in sheep, only three genes have been described encoding KAP1-1, ...
A nucleotide substitution in exon 8 of the glucosylceramidase beta gene is associated with Gaucher disease in sheep
(Wiley on behalf of Stichting International Foundation for Animal Genetics and the International Society for Animal Genetics, 2017-12)
Gaucher disease is an autosomal recessive disorder caused by deficiency of the enzyme glucosylceramidase beta (GBA; EC 3.2.1.45). Human Gaucher disease is caused by mutations in the GBA gene, and nearly 300 mutations have ...
Contrasting patterns of coding and flanking region evolution in mammalian keratin associated protein-1 genes
(Elsevier, 2019-04)
Mammalian genomes contain a number of duplicated genes, and sequence identity between these duplicates can be maintained by purifying selection. However, between-duplicate recombination can also maintain sequence identity ...
Identification of allelic polymorphism in the ovine leptin gene
(Springer, 2009)
Leptin is an adipocyte-derived hormone/cytokine that influences the physiological control of numerous biological functions and links nutritional status with both neuroendocrine and immune functions. In livestock, variation ...
Detection of sequence variation and genotyping of polymorphic genes using polymerase chain reaction stem-loop conformational polymorphism analysis
(Elsevier, 2011)
Here we describe a technique we have named polymerase chain reaction stem-loop conformational polymorphism (PCR-SLCP) analysis for screening DNA sequence variation. This technique uses PCR primers with adapters at the 5′ ...
Identification of the ovine KAP11-1 gene (KRTAP11-1) and genetic variation in its coding sequence
(Springer, 2011)
Keratin-associated proteins (KAPs) are a structural component of the wool fibre and form the matrix between the keratin intermediate filaments (KIFs). The gene encoding high sulphur-protein KAP11-1 has been identified in ...
Identification of caprine KRTAP28‐1 and its effect on cashmere fiber diameter
(MDPI, 2020-02-01)
The keratin‐associated proteins (KAPs) are constituents of cashmere fibers and variation in many KAP genes (KRTAPs) has been found to be associated with fiber traits. The gene encoding the high‐sulphur KAP28‐1 has been ...
Polymorphism of the ovine keratin-associated protein 1-4 gene (KRTAP1-4)
(2010-10-01)
Keratin-associated proteins (KAPs) are one of the main structural components of the wool fibre and form a semi-rigid matrix in which the keratin intermediate filaments are embedded. Variation in the KAP genes may affect ...
A nucleotide substitution in the ovine KAP20-2 gene leads to a premature stop codon that affects wool fibre curvature
(Wiley on behalf of Stichting International Foundation for Animal Genetics, 2018-08-01)
The keratin‐associated proteins (KAPs) form a matrix that cross‐links the main component of the wool fibre, the keratin intermediate filaments. They are therefore believed to play an important role in defining the physical ...
Identification and characterization of circular RNAs in mammary gland tissue from sheep at peak lactation and during the nonlactating period
(Elsevier Inc. and Fass Inc. on behalf of the American Dairy Science Association®, 2021-02-01)
Circular RNAs are a class of noncoding RNA with a widespread occurrence in eukaryote tissues, and with some having been demonstrated to have clear biological function. In sheep, little is known about the role of circular ...