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Identification of more than two paternal haplotypes of the ovine fatty acid-binding protein 4 (FABP4) gene in half-sib families: Evidence of intragenic meiotic recombination
(Public Library of Science, 2014-02-11)
The fatty acid binding protein 4 (FABP4) plays an important role in the regulation of lipid metabolism in mammals. In this study, two regions of ovine FABP4 spanning exon 2-intron 2 and exon 3-intron 3 were investigated ...
Identification of the ovine keratin-associated protein KAP1-2 gene (KRTAP1-2)
(John Wiley and Sons, 2011)
Abstract: Keratin-associated proteins (KAPs) are a major component of wool and other keratin-containing tissues. While four KAP1-n proteins have been identified in sheep, only three genes have been described encoding KAP1-1, ...
Genetic variation in the 5'UTR of the KRT2.13 gene of sheep
(Wiley on behalf of the Japanese Society of Animal Science, 2012-03)
KRT2.13 is a type II keratin wool intermediate filament (IF) protein. Extensive variation was revealed in the 5′ untranslated region (UTR) of the ovine KRT2.13 gene (KRT2.13) using polymerase chain reaction – single strand ...
Halplotypes of the ovine ADRB3 gene (ADRB3) and their association with post-weaning growth in New Zealand Suffolk sheep
(Springer Netherlands, 2013-08)
The β3-adrenergic receptor (ADRB3) regulates thermogenesis and lipolysis in brown and white adipose tissue. Previously, sixteen ovine ADRB3 haplotypes have been defined. In this study, the relationship between these ADRB3 ...
A nucleotide substitution in exon 8 of the glucosylceramidase beta gene is associated with Gaucher disease in sheep
(Wiley on behalf of Stichting International Foundation for Animal Genetics and the International Society for Animal Genetics, 2017-12)
Gaucher disease is an autosomal recessive disorder caused by deficiency of the enzyme glucosylceramidase beta (GBA; EC 3.2.1.45). Human Gaucher disease is caused by mutations in the GBA gene, and nearly 300 mutations have ...
Polymorphism in the ovine keratin-associated protein gene KRTAP7-1 and its association with wool characteristics
(Oxford University Press on behalf of the American Society of Animal Science, 2020-01)
The keratin-associated proteins (KAPs) are structural components of wool fibers and variation in the genes encoding the KAPs can affect wool traits. In this study, sequence variation in the ovine KAP7-1 gene (KRTAP7-1) was ...
Contrasting patterns of coding and flanking region evolution in mammalian keratin associated protein-1 genes
(Elsevier, 2019-04)
Mammalian genomes contain a number of duplicated genes, and sequence identity between these duplicates can be maintained by purifying selection. However, between-duplicate recombination can also maintain sequence identity ...
Identification of a Fusobacterium necrophorum isolate that contains a new variant of the leukotoxin gene (lktA) from the hoof of a sheep with ovine footrot
(Elsevier, 2011-05-05)
The finding of previously un-identified variant forms of the leukotoxin gene (lktA) from Fusobacterium necrophorum (F. necrophorum) isolates retrieved from the hooves of sheep, goats and cattle with footrot (Zhou et al., ...
Haplotyping using a combination of polymerase chain reaction–single-strand conformational polymorphism analysis and haplotype-specific PCR amplification
(Elsevier, 2014-12-01)
A single nucleotide polymorphism (SNP) may have an impact on phenotype, but it may also be influenced by multiple SNPs within a gene; hence, the haplotype or phase of multiple SNPs needs to be known. Various methods for ...
Identification of allelic polymorphism in the ovine leptin gene
(Springer, 2009)
Leptin is an adipocyte-derived hormone/cytokine that influences the physiological control of numerous biological functions and links nutritional status with both neuroendocrine and immune functions. In livestock, variation ...