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Genetic variation in the 5'UTR of the KRT2.13 gene of sheep
(Wiley on behalf of the Japanese Society of Animal Science, 2012-03)
KRT2.13 is a type II keratin wool intermediate filament (IF) protein. Extensive variation was revealed in the 5′ untranslated region (UTR) of the ovine KRT2.13 gene (KRT2.13) using polymerase chain reaction – single strand ...
A nucleotide substitution in exon 8 of the glucosylceramidase beta gene is associated with Gaucher disease in sheep
(Wiley on behalf of Stichting International Foundation for Animal Genetics and the International Society for Animal Genetics, 2017-12)
Gaucher disease is an autosomal recessive disorder caused by deficiency of the enzyme glucosylceramidase beta (GBA; EC 3.2.1.45). Human Gaucher disease is caused by mutations in the GBA gene, and nearly 300 mutations have ...
Polymorphism in the ovine keratin-associated protein gene KRTAP7-1 and its association with wool characteristics
(Oxford University Press on behalf of the American Society of Animal Science, 2020-01)
The keratin-associated proteins (KAPs) are structural components of wool fibers and variation in the genes encoding the KAPs can affect wool traits. In this study, sequence variation in the ovine KAP7-1 gene (KRTAP7-1) was ...
Effects of calcium chloride, zinc chloride and water infusion on metmyoglobbin reducing activity and fresh lamb colour
(American Society of Animal Science, 2005)
Calcium chloride (CaCl2), zinc chloride (ZnCl2), or water infusions were used to investigate the biochemical factors that affect fresh lamb color, and to examine the role of metmyoglobin-reducing activity in regulating ...
Two single nucleotide polymorphisms in the promoter of the ovine myostatin gene (MSTN) and their effect on growth and carcass muscle traits in New Zealand Romney sheep
(Wiley, 2016-06)
Myostatin is a negative regulator of muscle growth and development in mammals, and variation in ovine myostatin gene (MSTN) has been demonstrated to be associated with variation in the muscularity of sheep. Polymerase chain ...
Genetic variation in the ovine uncoupling protein 1 gene: Association with carcass traits in New Zealand (NZ) Romney sheep, but no association with growth traits in either NZ Romney or NZ Suffolk sheep
(Wiley, 2014-12)
The uncoupling protein 1 (UCP1) plays an important role in the regulation of lipolysis and thermogenesis in adipose tissues. Genetic variation within three regions (the promoter, intron 2 and exon 5) of the ovine UCP1 gene ...
A nucleotide substitution in the ovine KAP20-2 gene leads to a premature stop codon that affects wool fibre curvature
(Wiley on behalf of Stichting International Foundation for Animal Genetics, 2018-08-01)
The keratin‐associated proteins (KAPs) form a matrix that cross‐links the main component of the wool fibre, the keratin intermediate filaments. They are therefore believed to play an important role in defining the physical ...