Publication

Effect of immune stress on growth performance and immune functions of livestock: Mechanisms and prevention

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Authors
Niu, Xueting, Ding, Yuexia, Chen, Shengwei, Gooneratne, Ravi, Ju, Xianghong
Date
2022-04
Type
Journal Article
Collections
Department of Wine, Food and Molecular Biosciences
Keywords
growth performance, immune function, immune stress, mechanisms, prevention
Fields of Research
ANZSRC::300301 Animal growth and development, ANZSRC::300304 Animal protection (incl. pests and pathogens), ANZSRC::410407 Wildlife and habitat management, ANZSRC::410202 Biosecurity science and invasive species ecology, ANZSRC::310301 Behavioural ecology, ANZSRC::3003 Animal production, ANZSRC::3009 Veterinary sciences, ANZSRC::3109 Zoology
Abstract
Immune stress markedly affects the immune function and growth performance of livestock, including poultry, resulting in financial loss to farmers. It can lead to decreased feed intake, reduced growth, and intestinal disorders. Studies have shown that pathogen-induced immune stress is mostly related to TLR4-related inflammatory signal pathway activation, excessive inflammatory cytokine release, oxidative stress, hormonal disorders, cell apoptosis, and intestinal microbial disorders. This paper reviews the occurrence of immune stress in livestock, its impact on immune function and growth performance, and strategies for immune stress prevention.
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Permalink
https://hdl.handle.net/10182/15286
Source DOI
10.3390/ani12070909
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© 2022 The authors. Licensee MDPI, Basel, Switzerland
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