Diphacinone and coumatetralyl persistence in deer and implications for wildlife management
Eason, Charles; Murphy, E.; Ross, James G.; Hix, S.; Arthur, D.; MacMorran, D.; Broome, K.; Fairweather, A.
Abstract
Because of the concerns regarding wildlife contamination following the field use of anticoagulants the hepatic persistence of diphacinone and coumatetralyl has been compared in deer. Initial coumatetralyl concentrations in liver following oral dosing with 8.25 mg/kg coumatetralyl were similar on day 1 to those achieved by administration of diphacinone at 1.5 mg/kg. Coumatetralyl was more slowly eliminated (t½ 14 days) than diphacinone (t½ 6 days) and residues were still present in liver tissue after
50 days versus 12 days for diphacinone. Bioaccumulation on repeated field use is unlikely.
Keywords
coumatetralyl; deer; diphacinone; persistence; pharmacokinetics; residuesFields of Research
070205 Animal Protection (Pests and Pathogens); 050211 Wildlife and Habitat Management; 0608 ZoologyDate
2011-10-14Type
Conference Contribution - Published (Conference Abstract)Collections
© The authors