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dc.contributor.authorEmami-Khoyi, A.en
dc.contributor.authorParbhu, S. P.en
dc.contributor.authorRoss, James G.en
dc.contributor.authorMurphy, Elaineen
dc.contributor.authorBothwell, Jennen
dc.contributor.authorMonsanto, D. M.en
dc.contributor.authorvan Vuuren, B. J.en
dc.contributor.authorTeske, P. R.en
dc.contributor.authorPaterson, Adrian M.en
dc.date.accessioned2020-05-22T01:09:27Z
dc.date.available2020-04-17en
dc.date.issued2020-04-01en
dc.identifier.urihttps://hdl.handle.net/10182/11910
dc.description.abstractThe common brushtail possum (Trichosurus vulpecula), introduced from Australia in the mid-nineteenth century, is an invasive species in New Zealand where it is widespread and forms the largest self-sustained reservoir of bovine tuberculosis (Mycobacterium bovis) among wild populations. Conservation and agricultural authorities regularly apply a series of population control measures to suppress brushtail possum populations. The evolutionary consequence of more than half a century of intensive population control operations on the species’ genomic diversity and population structure is hindered by a paucity of available genomic resources. This study is the first to characterise the functional content and diversity of brushtail possum liver and brain cerebral cortex transcriptomes. Raw sequences from hepatic cells and cerebral cortex were assembled into 58,001 and 64,735 transcripts respectively. Functional annotation and polymorphism assignment of the assembled transcripts demonstrated a considerable level of variation in the core metabolic pathways that represent potential targets for selection pressure exerted by chemical toxicants. This study suggests that the brushtail possum population in New Zealand harbours considerable variation in metabolic pathways that could potentially promote the development of tolerance against chemical toxicants.en
dc.format.extent18en
dc.language.isoenen
dc.publisherMDPIen
dc.relationThe original publication is available from - MDPI - https://doi.org/10.3390/genes11040436en
dc.relation.urihttps://doi.org/10.3390/genes11040436en
dc.rights© 2020 by the authors.en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectDe novo transcriptome assemblyen
dc.subjectcommon brushtail possumen
dc.subjectliveren
dc.subjectbrain cerebral cortexen
dc.subjectdrug and xenobiotic metabolismen
dc.subjectchemical toxicantsen
dc.titleDe novo transcriptome assembly and annotation of liver and brain tissues of common brushtail possums (Trichosurus vulpecula) in New Zealand: Transcriptome diversity after decades of population controlen
dc.typeJournal Article
lu.contributor.unitLincoln Universityen
lu.contributor.unitFaculty of Agriculture and Life Sciencesen
lu.contributor.unitDepartment of Pest Management and Conservationen
dc.identifier.doi10.3390/genes11040436en
dc.subject.anzsrc050103 Invasive Species Ecologyen
dc.subject.anzsrc06 Biological Sciencesen
dc.subject.anzsrc0601 Biochemistry and Cell Biologyen
dc.subject.anzsrc060802 Animal Cell and Molecular Biologyen
dc.subject.anzsrc0604 Geneticsen
dc.relation.isPartOfGenesen
pubs.issue4en
pubs.notesArticle ID 436 Communication Accepted 10 April 2020en
pubs.organisational-group/LU
pubs.organisational-group/LU/Agriculture and Life Sciences
pubs.organisational-group/LU/Agriculture and Life Sciences/ECOL
pubs.organisational-group/LU/Research Management Office
pubs.organisational-group/LU/Research Management Office/PE20
pubs.organisational-group/LU/Research Management Office/QE18
pubs.publication-statusPublisheden
pubs.volume11en
dc.identifier.eissn2073-4425en
dc.rights.licenceAttributionen
dc.rights.licenceAttributionen
lu.identifier.orcid0000-0003-4090-0815
lu.identifier.orcid0000-0001-7413-4704


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