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dc.contributor.authorLi, Yunhaien
dc.contributor.authorZhou, Huitongen
dc.contributor.authorCheng, L.en
dc.contributor.authorZhao, Jenny H.en
dc.contributor.authorHickford, Jonathan G. H.en
dc.date.accessioned2021-03-02T01:31:45Z
dc.date.available2020-11-03en
dc.date.issued2020-11-03en
dc.date.submitted2020-09-03en
dc.identifier.issn0003-9438en
dc.identifier.urihttps://hdl.handle.net/10182/13495
dc.description.abstractGene markers have become useful tools for improving animal genetics and breeding since they improve the accuracy of selection for superior breeding stock. In this study, the stearoyl-CoA desaturase (Δ-9-desaturase) gene (SCD) was investigated in New Zealand pasture-grazed Holstein-Friesian × Jersey cows. Three nucleotide substitutions were identified in exon 5 of the gene (c.702A/G, c.762T/C and c.878C/T), and a single nucleotide substitution was identified in intron 5 (c.880C105A/G). The c.878C/T substitution would, if expressed, result in the amino acid substitution p.A293V. Four nucleotide substitutions (c.∗1783A/G, c.∗1883C/T, c.∗1984G/A and c.∗2066T/C/G) were identified in the 30-untranslated region (3′-UTR), and these resulted in three nucleotide sequence variants (named a, b and c). The sequence that would encode valine (V) at position 293 of SCD was linked to 3′-UTR variant a, and the sequence that would encode alanine (A) was linked to variants b and c. The frequency of the genotypes was as follows: VV (equivalent to aa: 15.1 %), VA (equivalent to ab C ac: 50.0 %) and AA (equivalent to bb C cc C bc: 34.9 %). The cows with the V variant produced less C10:1, C12:1 and C14:1 fatty acid (FA) but more C10:0, C11:0, C14:0, C16:1 and C18:2 FA than the A variant cows (P < 0.001). Effects of c.∗1783A/G and c.∗2066T/C/G on milk fat composition were also found for the AA cows. The presence of c was associated with decreased levels of C16:1 (P < 0.001), C17:1 (P D 0.001), C18:2 cis-9, trans-13 (P D 0.045), C18:2 cis-9, trans-12 (P D 0:018) FA and C16:1 FA index (P < 0.001). The presence of b was associated with increased levels of C13:0 iso FAs (P < 0.001), monounsaturated FA (MUFA; P D 0.002) and C12:1 (P < 0.001).en
dc.format.extent355-366en
dc.languageenen
dc.language.isoenen
dc.publisherCopernicus Publications on behalf of the Leibniz Institute for Farm Animal Biology (FBN)en
dc.relationThe original publication is available from - Copernicus Publications on behalf of the Leibniz Institute for Farm Animal Biology (FBN) - https://doi.org/10.5194/aab-63-355-2020en
dc.relation.urihttps://doi.org/10.5194/aab-63-355-2020en
dc.rights© Author(s) 2020.en
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectgeneen
dc.subjectlactateen
dc.subjectdairy cattleen
dc.subjectStearoyl-CoA desaturase (SCD)en
dc.subjectfatty acidsen
dc.subjectmilken
dc.subjectDairy & Animal Scienceen
dc.titleVariation in the stearoyl-CoA desaturase gene (SCD) and its influence on milk fatty acid composition in late-lactation dairy cattle grazed on pastureen
dc.typeJournal Article
lu.contributor.unitLincoln Universityen
lu.contributor.unitFaculty of Agriculture and Life Sciencesen
lu.contributor.unitDepartment of Agricultural Sciencesen
dc.identifier.doi10.5194/aab-63-355-2020en
dc.subject.anzsrc0702 Animal Productionen
dc.subject.anzsrc070202 Animal Growth and Developmenten
dc.subject.anzsrc070201 Animal Breedingen
dc.subject.anzsrc100104 Genetically Modified Animalsen
dc.subject.anzsrc0701 Agriculture, Land and Farm Managementen
dc.relation.isPartOfArchives Animal Breeding (AAB)en
pubs.issue2en
pubs.organisational-group/LU
pubs.organisational-group/LU/Agriculture and Life Sciences
pubs.organisational-group/LU/Agriculture and Life Sciences/AGSC
pubs.organisational-group/LU/Research Management Office
pubs.organisational-group/LU/Research Management Office/QE18
pubs.publication-statusPublished onlineen
pubs.volume63en
dc.identifier.eissn2363-9822en
dc.rights.licenceAttributionen
dc.rights.licenceAttributionen
lu.identifier.orcid0000-0001-9313-761X
lu.identifier.orcid0000-0001-7620-3160


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