Now showing items 1-5 of 5
Mathematical modelling of the core regulatory feedback mechanisms of p53 protein that decide cell fate
(Lincoln University, 2014)
Cells defence against stresses that can cause DNA damage (single-strand breaks, double-strand breaks) is crucial in safeguarding the integrity of the genome and the survival of the organism as a whole. One of the genes ...
Remodelling circadian rhythm in Drosophila melanogaster: to investigate the role of a new clock component clockwork orange (CWO)
(Lincoln University, 2015)
The ability of almost all organisms to change their behaviour on a daily basis is one of the remarkable features of life on earth. This phenomenon which is called circadian rhythm is observed in diverse organisms such as ...
A systems approach to identifying correlated gene targets for the loss of colour pigmentation in plants
(BMC Bioinformatics., 2011)
The numerous diverse metabolic pathways by which plant compounds can be produced make it difficult to predict how colour pigmentation is lost for different tissues and plants. This study employs mathematical and in silico ...
Computational techniques in mathematical modelling of biological switches
Mathematical models of biological switches have been proposed as a means to study the mechanism of decision making in biological systems. These conceptual models are abstract representations of the key components involved ...
Modelling calmodulin dependent calcium signalling involved with synaptic plasticity : A thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Lincoln University
(Lincoln University, 2018)
Neurotransmission of synapses is plastic in that they get modulated to increase or decrease conductivity (this is known as synaptic plasticity). Synaptic plasticity consists of two opposing forces: long term potentiation ...