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dc.contributor.authorKenyon, F.en
dc.contributor.authorMcBean, D.en
dc.contributor.authorGreer, Andrew W.en
dc.contributor.authorBurgess, C. G. S.en
dc.contributor.authorMorrison, A. A.en
dc.contributor.authorBartley, D. J.en
dc.contributor.authorBartley, Y.en
dc.contributor.authorDevin, L.en
dc.contributor.authorNath, M.en
dc.contributor.authorJackson, F.en
dc.date.accessioned2016-08-19T02:20:47Z
dc.date.available2013-03-06en
dc.date.issued2013-12en
dc.date.submitted2013-02-18en
dc.identifier.citationKenyon et al. (2013). A comparative study of the effects of four treatment regimes on ivermectin efficacy, body weight and pasture contamination in lambs naturally infected with gastrointestinal nematodes in Scotland. International Journal for Parasitology: Drugs and Drug Resistance, 3, 77-84. doi 10.1016/j.ijpddr.2013.02.001en
dc.identifier.issn2211-3207en
dc.identifier.urihttps://hdl.handle.net/10182/7253
dc.description.abstractRefugia-based drenching regimes have been widely recommended to slow development of anthelmintic resistance but there are few comparisons between different treatment approaches in the UK. The impact of four ivermectin treatment regimes on drug efficacy, lamb body weight and nematode contamination during a 154 day grazing season were evaluated in a consecutive five year field study. Regimes were whole-flock treatment every 4 weeks (NST), targeted selective treatment (TST) based on individual performance, strategic whole-flock treatments at pre-determined times (SPT) or whole-flock treatment when clinical signs were apparent (MT). Mean numbers of ivermectin drenches administered per season were 4.0, 1.8, 2.0 and 1.4 for NST, TST, SPT and MT groups, respectively. The mean anthelmintic efficacy (AE) for each treatment group was based on faecal egg count reduction post-treatment employing a bootstrap sampling based algorithm. Mean AE was 95–98% for all groups in 2006 and mean AE (95% confidence limits) for NST declined to 62% (55%, 68%) in 2010. In comparison, AE for TST, SPT and MT in 2010 were 86% (81%, 92%), 86% (83%, 90%) and 83% (78%, 88%), respectively. Body weight in TST and SPT was similar to NST in all years (p > 0.05), however MT lambs were lighter than NST in 2006–2008 (p ⩽ 0.04). Tracer lamb worm burdens was lowest in NST but was not significantly different between other groups. Overall, both the TST and SPT regimes appeared to maintain animal performance and conserve anthelmintic efficacy compared with a neo-suppressive anthelmintic treatment regime.en
dc.format.extent77-84en
dc.language.isoenen
dc.publisherElsevieren
dc.relationThe original publication is available from - Elsevier - https://doi.org/10.1016/j.ijpddr.2013.02.001 - http://www.sciencedirect.com/science/article/pii/S2211320713000067en
dc.relation.urihttps://doi.org/10.1016/j.ijpddr.2013.02.001en
dc.rights© 2013 Australian Society for Parasitology Published by Elsevier Ltd. All rights reserved.en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectSheepen
dc.subjectGastrointestinal nematodesen
dc.subjectAnthelmintic resistanceen
dc.subjectRefugiaen
dc.subjectLambsen
dc.titleA comparative study of the effects of four treatment regimes on ivermectin efficacy, body weight and pasture contamination in lambs naturally infected with gastrointestinal nematodes in Scotlanden
dc.typeJournal Article
lu.contributor.unitLincoln Universityen
lu.contributor.unitFaculty of Agriculture and Life Sciencesen
lu.contributor.unitDepartment of Agricultural Sciencesen
dc.identifier.doi10.1016/j.ijpddr.2013.02.001en
dc.subject.anzsrc070202 Animal Growth and Developmenten
dc.subject.anzsrc070205 Animal Protection (Pests and Pathogens)en
dc.relation.isPartOfInternational Journal for Parasitology: Drugs and Drug Resistanceen
pubs.organisational-group/LU
pubs.organisational-group/LU/Agriculture and Life Sciences
pubs.organisational-group/LU/Agriculture and Life Sciences/AGSC
pubs.organisational-group/LU/Research Management Office
pubs.organisational-group/LU/Research Management Office/QE18
pubs.publication-statusPublisheden
pubs.publisher-urlhttp://www.sciencedirect.com/science/article/pii/S2211320713000067en
pubs.volume3en
dc.rights.licenceAttribution-NonCommercial-NoDerivativesen
lu.identifier.orcid0000-0002-1479-3297


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