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dc.contributor.authorMuangphra, P.en
dc.contributor.authorGooneratne, Sarojith R.en
dc.date.accessioned2017-11-20T02:16:34Z
dc.date.issued2011en
dc.identifier.citationMuangphra, P., & Gooneratne, R. (2011). Comparative genotoxicity of cadmium and lead in earthworm coelomocytes. Applied and Environmental Soil Science, 2011, 218929. doi:10.1155/2011/218929en
dc.identifier.issn1687-7667en
dc.identifier.urihttps://hdl.handle.net/10182/8764
dc.description.abstractTo determine genotoxicity to coelomocytes, Pheretima peguana earthworms were exposed in filter paper studies to cadmium (Cd) and lead (Pb) for 48 h, at concentrations less than the LC₁₀—Cd: 0.09, 0.19, 0.38, 0.75, and 1.50 µg cm⁻²; Pb: 1.65, 3.29, 6.58, 13.16, and 26.32 µg cm⁻². For Cd at 0.75 µg cm⁻², in the micronucleus test (detects chromosomal aberrations), significant increases (P < .05) in micronuclei and binucleate cells were observed, and in the comet assay (detects DNA single-strand breaks), tail DNA% was significantly increased. Lead was less toxic with minimal effects on DNA, but the binucleates were significantly increased by Pb at 3.29 µg cm⁻². This study shows that Cd is more acutely toxic and sublethally genotoxic than Pb to P. peguana. Cadmium caused chromosomal aberrations and DNA single-strand breaks at 45% of the LC₁₀ concentration. Lead, in contrast, did not induce DNA damage but caused cytokinesis defects.en
dc.format.extent7en
dc.language.isoenen
dc.publisherHindawi Publishing Corporationen
dc.relationThe original publication is available from - Hindawi Publishing Corporation - https://doi.org/10.1155/2011/218929en
dc.relation.urihttps://doi.org/10.1155/2011/218929en
dc.rights© 2011. P. Muangphra and R. Gooneratne. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectPheretima peguanaen
dc.subjectearthwormsen
dc.subjectsoil toxicityen
dc.subjectcadmiumen
dc.subjectleaden
dc.subjectcytokinesisen
dc.subjectDNAen
dc.subjectgenotoxicityen
dc.subjectcoelomocytesen
dc.titleComparative genotoxicity of cadmium and lead in earthworm coelomocytesen
dc.typeJournal Article
lu.contributor.unitLincoln Universityen
lu.contributor.unitFaculty of Agriculture and Life Sciencesen
lu.contributor.unitDepartment of Wine, Food and Molecular Biosciencesen
lu.contributor.uniten
lu.contributor.uniten
dc.identifier.doi10.1155/2011/218929en
dc.subject.anzsrc060808 Invertebrate Biologyen
dc.subject.anzsrc0503 Soil Sciencesen
dc.relation.isPartOfApplied and Environmental Soil Scienceen
pubs.notesArticle ID 218929 Date of acceptance: 11 Mar 2017en
pubs.organisational-group/LU
pubs.organisational-group/LU/Agriculture and Life Sciences
pubs.organisational-group/LU/Agriculture and Life Sciences/WFMB
pubs.organisational-group/LU/Research Management Office
pubs.organisational-group/LU/Research Management Office/2018 PBRF Staff group
pubs.publication-statusPublisheden
pubs.volume2011en
dc.identifier.eissn1687-7675en
dc.rights.licenceAttributionen
lu.identifier.orcid0000-0002-5406-2894


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