Burrow, KeeganYoung, Wayne,McConnell, MCarne, ABarr, DReid, Malcolm,Bekhit, AE-D2020-03-082020-02-252020-032020-02-222072-664332106433 (pubmed)https://hdl.handle.net/10182/11551The aim of this study was to investigate the effect of either sheep or cow milk supplementation to a low calcium and phosphorus diet on growth and organ mineral distribution in weanling rats. Rats were fed diets consisting of either a control chow, a 50% reduced calcium and phosphorous chow (low Ca/P), low Ca/P and sheep milk, or low Ca/P and cow milk diet for 28 days. Food intake of the rats, the growth rate of the rats, and the concentrations of minerals in the soft organs and serum were determined. Rats fed the low Ca/P diet alone had lower weight gain than rats consuming either of the milk-supplemented diets (p < 0.05). Both sheep milk and cow milk supplementation overcame the effects of consuming a diet restricted in calcium and phosphorus but the sheep milk was effective at a significantly lower level of milk intake (p < 0.05). Significant differences (p < 0.05) in essential and trace mineral concentrations due to milk type were observed in the kidney, spleen, and liver. For non-essential minerals, significant differences (p < 0.05), related to diet, were observed in all organs for arsenic, cesium, rubidium, and strontium concentrations.16 pagesElectronicen© 2020 by the authors. Licensee MDPI, Basel, Switzerland.milkmacro-mineralstrace-mineralsICP-MSsheep milkcow milkcalciumphosphoroussoft organsphosphorusMilkAnimalsCattleSheepHumansRatsDeficiency DiseasesDisease Models, AnimalCalcium, DietaryPhosphatesCalciumTrace ElementsWeaningFemaleMaleJournal Article10.3390/nu12030594ANZSRC::111103 Nutritional PhysiologyANZSRC::111102 Dietetics and NutrigenomicsANZSRC::070204 Animal Nutrition2072-6643ANZSRC::3202 Clinical sciencesANZSRC::3210 Nutrition and dieteticsANZSRC::4206 Public healthhttps://creativecommons.org/licenses/by/4.0/Attribution