Rajendran, KWalsh, MFde Ruiter, NJAChernoglazov, AIPanta, RKButler, APHButler, PHBell, STAnderson, NGWoodfield, TBFTredinnick, SJHealy, JLBateman, CJAamir, RDoesburg, RMNRenaud, PFGieseg, SPSmithies, DJMohr, JLMandalika, VBHOpie, AMTCook, NJRonaldson, JPNik, SJAtharifard, AClyne, MBones, PJBartneck, CGrasset, RSchleich, NBillinghurst, M2018-04-272014-03-262014-032014-02-11Rajendran et al. (2014). Reducing beam hardening effects and metal artefacts in spectral CT using Medipix3RX. Journal of Instrumentation, 9, P03015-P03015. doi:10.1088/1748-0221/9/03/P030151748-0221AH4UE (isidoc)https://hdl.handle.net/10182/9284This paper discusses methods for reducing beam hardening effects and metal artefacts using spectral x-ray information in biomaterial samples. A small-animal spectral scanner was operated in the 15 to 80 keV x-ray energy range for this study. We use the photon-processing features of a CdTe-Medipix3RX ASIC in charge summing mode to reduce beam hardening and associated artefacts. We present spectral data collected for metal alloy samples, its analysis using algebraic 3D reconstruction software and volume visualisation using a custom volume rendering software. The cupping effect and streak artefacts are quantified in the spectral datasets. The results show reduction in beam hardening effects and metal artefacts in the narrow high energy range acquired using the spectroscopic detector. A post reconstruction comparison between CdTe-Medipix3RX and Si-Medipix3.1 is discussed. The raw data and processed data are made available (http://hdl.handle.net/10092/8851) for testing with other software routines.13 pagesen© CERN 2014, published under the terms of the Creative Commons Attribution 3.0 License by IOP Publishing Ltd and Sissa Medialab srl. Any further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation and DOI.medical-image reconstruction methods and algorithmscomputer-aided diagnosisX-ray detectorscomputerized tomography (CT)computed Radiography (CR)Reducing beam hardening effects and metal artefacts in spectral CT using Medipix3RXJournal Article10.1088/1748-0221/9/03/P03015ANZSRC::020203 Particle PhysicsANZSRC::11 Medical and Health Sciences1748-0221ANZSRC::40 EngineeringANZSRC::51 Physical scienceshttps://creativecommons.org/licenses/by/4.0/Attribution