Variation in the Yak calpastatin gene (CAST)

Simple item page
dc.contributor.authorYang, G.
dc.contributor.authorZhou, Huitong
dc.contributor.authorHu, J.
dc.contributor.authorLuo, Y.
dc.contributor.authorHickford, Jonathan G. H.
dc.date.accessioned2015-06-04T04:09:59Z
dc.date.issued2012
dc.description.abstractCalpastatin (CAST) is a specific inhibitor of calpain (calcium-dependent cysteine protease). This study investigated the potential for variation in yak (Bos grennies) CAST. PCR-SSCP analysis of exon 6 of yak CAST revealed three unique patterns (named A-C). Sequencing of the amplicons revealed two nucleotide substitutions. One substitution (c.398G/C) would nominally change the amino acid sequence (p.S133T) of yak calpastatin. The variant sequence A which carried c.398C was the most common in the yaks tested (95.1%). This is the first report that found yak CAST is variable, and as in pigs, sheep and cattle, this variation may affect animal production traits.en
dc.format.extent72-73en
dc.identifier.citationYang G., Zhou H., Hu J., Luo Y. & Hickford, J.G.H. (2012). Variation in the yak calpastatin gene (CAST). International Journal of Genetics, 4(1) pp.-72-73.
dc.identifier.eissn0975-9158en
dc.identifier.issn0975-2862en
dc.identifier.urihttps://hdl.handle.net/10182/6581
dc.language.isoen
dc.publisherBioinfo Publications
dc.publisher.placeUSAen
dc.relationThe original publication is available from - Bioinfo Publications - http://www.bioinfo.in/uploadfiles/13330165644_1_1_IJG.pdfen
dc.relation.isPartOfInternational Journal of Geneticsen
dc.rightsCopyright©2012 Yang G., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.rights.ccnameAttributionen
dc.rights.ccurihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectCASTen
dc.subjectgenetic variationen
dc.subjectYak (Bos grennies)en
dc.subjectPCR- single strand conformational polymorphism (PCR-SSCP)en
dc.subject.anzsrcANZSRC::0604 Geneticsen
dc.subject.anzsrcANZSRC::060602 Animal Physiology - Cellen
dc.titleVariation in the Yak calpastatin gene (CAST)en
dc.typeJournal Article
lu.contributor.unitLincoln University
lu.contributor.unitFaculty of Agriculture and Life Sciences
lu.contributor.unitDepartment of Agricultural Sciences
lu.identifier.orcid0000-0001-9313-761X
lu.identifier.orcid0000-0001-7620-3160
pubs.issue1en
pubs.publication-statusPublisheden
pubs.publisher-urlhttp://www.bioinfo.in/uploadfiles/13330165644_1_1_IJG.pdfen
pubs.volume4en
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
4_1_1_IJG.pdf
Size:
273.46 KB
Format:
Adobe Portable Document Format
Name: 4_1_1_IJG.pdf
Size: 273.46 KB
Kind: Adobe PDF
Licence bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Deposit Licence (LURA).pdf
Size:
11.02 KB
Format:
Adobe Portable Document Format
Description:
Name: Deposit Licence (LURA).pdf
Size: 11.02 KB
Kind: Adobe PDF
Collections
Department of Agricultural Sciences