Variation in the ovine KAP6-3 gene (KRTAP6-3) is associated with variation in mean fibre diameter-associated wool traits
dc.contributor.author | Li, S | |
dc.contributor.author | Zhou, Huitong | |
dc.contributor.author | Gong, H | |
dc.contributor.author | Zhao, F | |
dc.contributor.author | Wang, J | |
dc.contributor.author | Luo, Y | |
dc.contributor.author | Hickford, Jonathan | |
dc.coverage.spatial | Switzerland | |
dc.date.accessioned | 2017-11-03T02:52:28Z | |
dc.date.available | 2017-08-18 | |
dc.date.issued | 2017 | |
dc.date.submitted | 2017-08-17 | |
dc.description.abstract | Polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) analysis was used to investigate variation in the ovine KAP6-3 gene (KRTAP6-3) in 383 Merino × Southdown-cross lambs from four sire-lines, and to determine whether this variation affects wool traits. Five PCR-SSCP banding patterns, representing five different nucleotide sequences, were detected, including four previously identified (named A, B, C, and F) variants and one newly identified (named G) variant. A new non-synonymous single nucleotide polymorphism (SNP) and a 45-bp deletion were detected in variant G. Of the three common genotypes (AA, AB, and AG) identified in these sheep, wool from sheep that were AG, on average, had a lower mean fibre diameter (MFD), fibre diameter standard deviation (FDSD), and prickle factor (PF) than wool from AA sheep, whereas wool from AB sheep, on average, had a higher MFD, FDSD, and PF than wool from AA sheep. This suggests that variation in ovine KRTAP6-3 affect MFD, FDSD, and PF, and that this gene may have potential for use as a gene-maker for improving fibre diameter-associated wool traits. | |
dc.format.extent | 9 pages | |
dc.format.medium | Electronic | |
dc.identifier | genes8080204 | |
dc.identifier | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=elements_prod&SrcAuth=WosAPI&KeyUT=WOS:000408851200013&DestLinkType=FullRecord&DestApp=WOS_CPL | |
dc.identifier.citation | Li, S., Zhou, H., Gong, H., Zhao, F., Wang, J., Luo, Y., & Hickford, J.G.H. (2017). Variation in the ovine KAP6-3 gene (KRTAP6-3) is associated with variation in mean fibre diameter-associated wool traits. Genes, 8(8), 204. doi:10.3390/genes8080204 | |
dc.identifier.doi | 10.3390/genes8080204 | |
dc.identifier.eissn | 2073-4425 | |
dc.identifier.issn | 2073-4425 | |
dc.identifier.other | FF3VT (isidoc) | |
dc.identifier.other | 28820492 (pubmed) | |
dc.identifier.uri | https://hdl.handle.net/10182/8725 | |
dc.language.iso | en | |
dc.publisher | MDPI AG | |
dc.relation | The original publication is available from MDPI AG - https://doi.org/10.3390/genes8080204 - http://dx.doi.org/10.3390/genes8080204 | |
dc.relation.isPartOf | Genes | |
dc.relation.uri | https://doi.org/10.3390/genes8080204 | |
dc.rights | This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0). | |
dc.rights.ccname | Attribution | |
dc.rights.ccuri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject | KAP6-3 gene (KRTAP6-3) | |
dc.subject | mean fibre diameter (MFD) | |
dc.subject | wool traits | |
dc.subject | sheep | |
dc.subject.anzsrc | ANZSRC::070201 Animal Breeding | |
dc.subject.anzsrc | ANZSRC::0604 Genetics | |
dc.subject.anzsrc2020 | ANZSRC::3105 Genetics | |
dc.title | Variation in the ovine KAP6-3 gene (KRTAP6-3) is associated with variation in mean fibre diameter-associated wool traits | |
dc.type | Journal Article | |
lu.contributor.unit | LU | |
lu.contributor.unit | LU|Agriculture and Life Sciences | |
lu.contributor.unit | LU|Agriculture and Life Sciences|AGSC | |
lu.contributor.unit | LU|Research Management Office | |
lu.contributor.unit | LU|Research Management Office|OLD QE18 | |
lu.contributor.unit | LU|Centre of Excellence for One Biosecurity Research, Analysis and Synthesis | |
lu.identifier.orcid | 0000-0001-7620-3160 | |
lu.identifier.orcid | 0000-0001-9313-761X | |
pubs.issue | 8 | |
pubs.notes | Article 204. Accepted 17 Aug 2017 | |
pubs.publication-status | Published | |
pubs.publisher-url | http://dx.doi.org/10.3390/genes8080204 | |
pubs.volume | 8 |
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