Associations between the bovine myostatin gene and milk fatty acid composition in New Zealand Holstein-Friesian × Jersey-cross cows
dc.contributor.author | Haruna, IL | |
dc.contributor.author | Li, Y | |
dc.contributor.author | Ekegbu, UJ | |
dc.contributor.author | Amirpour Najafabadi, H | |
dc.contributor.author | Zhou, Huitong | |
dc.contributor.author | Hickford, Jonathan | |
dc.coverage.spatial | Switzerland | |
dc.date.accessioned | 2021-01-28T03:27:38Z | |
dc.date.available | 2020-08-19 | |
dc.date.issued | 2020-09 | |
dc.date.submitted | 2020-08-15 | |
dc.description.abstract | The myostatin gene (MSTN), which encodes the protein myostatin, is pleiotropic, and its expression has been associated with both increased and decreased adipogenesis and increased skeletal muscle mass in animals. In this study, the polymerase chain reaction, coupled with single strand conformation polymorphism analysis, was utilized to reveal nucleotide sequence variation in bovine MSTN in 410 New Zealand (NZ) Holstein-Friesian × Jersey (HF × J)-cross cows. These cows ranged from 3 to 9 years of age and over the time studied, produced an average 22.53 ± 2.18 L of milk per day, with an average milk fat content of 4.94 ± 0.17% and average milk protein content of 4.03 ± 0.10%. Analysis of a 406-bp amplicon from the intron 1 region, revealed five nucleotide sequence variants (A–E) that contained seven nucleotide substitutions. Using general linear mixed-effect model analyses the AD genotype was associated with reduced C10:0, C12:0, and C12:1 levels when compared to levels in cows with the AA genotype. These associations in NZ HF × J cross cows are novel, and they suggest that this variation in bovine MSTN could be explored for increasing the amount of milk unsaturated fatty acid and decreasing the amount of saturated fatty acid. | |
dc.format.extent | 10 pages | |
dc.format.medium | Electronic | |
dc.identifier | ani10091447 | |
dc.identifier | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=elements_prod&SrcAuth=WosAPI&KeyUT=WOS:000580242800001&DestLinkType=FullRecord&DestApp=WOS_CPL | |
dc.identifier.doi | 10.3390/ani10091447 | |
dc.identifier.eissn | 2076-2615 | |
dc.identifier.issn | 2076-2615 | |
dc.identifier.other | OE0PC (isidoc) | |
dc.identifier.other | 32824948 (pubmed) | |
dc.identifier.uri | https://hdl.handle.net/10182/13299 | |
dc.language.iso | en | |
dc.publisher | MDPI | |
dc.relation | The original publication is available from MDPI - https://doi.org/10.3390/ani10091447 - http://dx.doi.org/10.3390/ani10091447 | |
dc.relation.isPartOf | Animals | |
dc.relation.uri | https://doi.org/10.3390/ani10091447 | |
dc.rights | © 2020 by the authors. Licensee MDPI, Basel, Switzerland. | |
dc.rights.ccname | Attribution | |
dc.rights.ccuri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject | myostatin gene | |
dc.subject | variation | |
dc.subject | milk | |
dc.subject | fatty acid | |
dc.subject | cattle | |
dc.subject.anzsrc | ANZSRC::0604 Genetics | |
dc.subject.anzsrc | ANZSRC::070202 Animal Growth and Development | |
dc.subject.anzsrc | ANZSRC::070201 Animal Breeding | |
dc.subject.anzsrc2020 | ANZSRC::3003 Animal production | |
dc.subject.anzsrc2020 | ANZSRC::3009 Veterinary sciences | |
dc.subject.anzsrc2020 | ANZSRC::3109 Zoology | |
dc.title | Associations between the bovine myostatin gene and milk fatty acid composition in New Zealand Holstein-Friesian × Jersey-cross cows | |
dc.type | Journal Article | |
lu.contributor.unit | LU | |
lu.contributor.unit | LU|Agriculture and Life Sciences | |
lu.contributor.unit | LU|Agriculture and Life Sciences|AGSC | |
lu.contributor.unit | LU|Research Management Office | |
lu.contributor.unit | LU|Research Management Office|OLD QE18 | |
lu.contributor.unit | LU|Centre of Excellence for One Biosecurity Research, Analysis and Synthesis | |
lu.identifier.orcid | 0000-0001-7620-3160 | |
lu.identifier.orcid | 0000-0001-9313-761X | |
pubs.article-number | 1447 | |
pubs.issue | 9 | |
pubs.notes | This article belongs to the Special Issue High-Yielding Dairy Cows | |
pubs.publication-status | Published | |
pubs.publisher-url | http://dx.doi.org/10.3390/ani10091447 | |
pubs.volume | 10 |
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