Identification of the association between FABP4 gene polymorphisms and milk production traits in Sfakia sheep
dc.contributor.author | Ibrahim, AHM | |
dc.contributor.author | Tzanidakis, N | |
dc.contributor.author | Sotiraki, S | |
dc.contributor.author | Zhou, Huitong | |
dc.contributor.author | Hickford, Jonathan | |
dc.coverage.spatial | Germany | |
dc.date.accessioned | 2019-07-31T23:56:11Z | |
dc.date.available | 2019-07-15 | |
dc.date.issued | 2019-07-15 | |
dc.date.submitted | 2019-06-17 | |
dc.description.abstract | The aim of this study was to estimate the effect of variation in the fatty acid binding protein 4 gene (FABP4) on milk production traits in Greek Sfakia sheep. Polymerase chain reaction – single-stranded conformational polymorphism (PCR-SSCP) analysis was used to genotype a total of 374 Sfakia ewes for two regions of FABP4 located around exon 2–intron 2 (Region 1) and exon 3–intron 3 (Region 2). Each month, for a period of 6 months, milk samples were collected from the ewes to measure total milk yield, fat content, protein content, lactose content, non-fat solid content, pH, and somatic cell count (SCC). A general linear model was used to test the association between the variation observed in FABP4 and milk production traits. Four gene variants (A1–A4) were found in Region 1 and two variants (C1–C2) were found in Region 2. In the first region, the FABP4 genotype significantly affected (P < 0.05) non-fat solid levels, fat content, and SCC. The presence of the A2 variant was significantly associated (P < 0.05) with decreased SCC, while the presence of A4 was significantly associated with decreased milk yield (P < 0.01), increased non-fat solid content (P < 0.05), decreased fat content (P < 0.01), increased lactose content (P < 0.05), and increased pH (P < 0.05). In the second region, FABP4 genotype had an effect (P < 0.05) on protein content and the presence of the C2 variant was associated (P < 0.05) with increased protein content, decreased SCC, and lower pH. The results suggest an association between variation in ovine FABP4 and milk production traits in Greek Sfakia sheep. Nevertheless, further analyses in independent sheep populations of increased size will strengthen these findings. | |
dc.format.extent | pp.413-422 | |
dc.format.medium | Electronic-eCollection | |
dc.identifier | 01021829 | |
dc.identifier | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=elements_prod&SrcAuth=WosAPI&KeyUT=WOS:000475465100001&DestLinkType=FullRecord&DestApp=WOS_CPL | |
dc.identifier.citation | Ibrahim, A.H.M., Tzanidakis, N., Sotiraki, S., Zhou, H., & Hickford, J.G.H. (2019). Identification of the association between FABP4 gene polymorphisms and milk production traits in Sfakia sheep. Archives Animal Breeding, 62(2), 413-422. doi:10.5194/aab-62-413-2019 | |
dc.identifier.doi | 10.5194/aab-62-413-2019 | |
dc.identifier.eissn | 2363-9822 | |
dc.identifier.issn | 0003-9438 | |
dc.identifier.other | II8TM (isidoc) | |
dc.identifier.other | 31807652 (pubmed) | |
dc.identifier.uri | https://hdl.handle.net/10182/10849 | |
dc.language.iso | en | |
dc.publisher | Copernicus Publications on behalf of the Leibniz Institute for Farm Animal Biology (FBN) | |
dc.relation | The original publication is available from Copernicus Publications on behalf of the Leibniz Institute for Farm Animal Biology (FBN) - https://doi.org/10.5194/aab-62-413-2019 - http://dx.doi.org/10.5194/aab-62-413-2019 | |
dc.relation.isPartOf | Archives Animal Breeding | |
dc.relation.uri | https://doi.org/10.5194/aab-62-413-2019 | |
dc.rights | © Author(s) 2019 | |
dc.rights.ccname | Attribution | |
dc.rights.ccuri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject | FABP4 gene | |
dc.subject | milk production | |
dc.subject | Sfakia sheep | |
dc.subject.anzsrc | ANZSRC::0702 Animal Production | |
dc.subject.anzsrc2020 | ANZSRC::3003 Animal production | |
dc.title | Identification of the association between FABP4 gene polymorphisms and milk production traits in Sfakia sheep | |
dc.type | Journal Article | |
lu.contributor.unit | LU | |
lu.contributor.unit | LU|Agriculture and Life Sciences | |
lu.contributor.unit | LU|Agriculture and Life Sciences|AGSC | |
lu.contributor.unit | LU|Research Management Office | |
lu.contributor.unit | LU|Research Management Office|OLD QE18 | |
lu.contributor.unit | LU|Centre of Excellence for One Biosecurity Research, Analysis and Synthesis | |
lu.identifier.orcid | 0000-0001-7620-3160 | |
lu.identifier.orcid | 0000-0001-9313-761X | |
pubs.issue | 2 | |
pubs.publication-status | Published | |
pubs.publisher-url | http://dx.doi.org/10.5194/aab-62-413-2019 | |
pubs.volume | 62 |
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