Brief communication: Performance of lambs exposed to a desensitising regime prior to infection with Trichostrongylus colubriformis

Abstract

Enhancing the immune response of lambs against the gastrointestinal nematode Trichostrongylus colubriformis through vaccination has been previously investigated (Windon et al. 1984; Douch 1989; McClure 2009). However, the majority of production loss from this parasite species in sheep has been attributed to components of the immune response (Greer et al. 2005). As such, manipulation of the host immune response through desensitisation may provide a novel method of reducing production loss associated with infection. The objective of this investigation was to evaluate the ability of a desensitising regime with parasite antigens to reduce the production cost associated with Trichostrongylus colubriformis infection in lambs