Genetic variation in the ovine uncoupling protein 1 gene: Association with carcass traits in New Zealand (NZ) Romney sheep, but no association with growth traits in either NZ Romney or NZ Suffolk sheep
dc.contributor.author | Yang, G | |
dc.contributor.author | Forrest, RH | |
dc.contributor.author | Zhou, Huitong | |
dc.contributor.author | Hodge, S | |
dc.contributor.author | Hickford, Jonathan | |
dc.coverage.spatial | Germany | |
dc.date.accessioned | 2017-03-27T03:05:10Z | |
dc.date.available | 2014-06-09 | |
dc.date.issued | 2014-12 | |
dc.date.submitted | 2014-04-30 | |
dc.description.abstract | The uncoupling protein 1 (UCP1) plays an important role in the regulation of lipolysis and thermogenesis in adipose tissues. Genetic variation within three regions (the promoter, intron 2 and exon 5) of the ovine UCP1 gene (UCP1) was investigated using polymerase chain reaction-single-strand conformational polymorphism (PCR-SSCP) analyses. These revealed three promoter variants (designated A, B and C) and two intron 2 variants (a and b). The association of this genetic variation with variation in lamb carcass traits and postweaning growth was investigated in New Zealand (NZ) Romney and Suffolk sheep. The presence of B in a lamb's genotype was associated with decreased subcutaneous carcass fat depth (V-GR) (p = 0.004) and proportion of total lean meat yield of loin meat (p = 0.005), and an increased proportion of total lean meat yield of hind-leg meat (p = 0.018). In contrast, having two copies of C was associated with increased V-GR (p < 0.001) and proportion of total lean meat yield of shoulder meat (p = 0.009), and a decreased hind-leg yield (p = 0.032). No associations were found with postweaning growth. These results suggest that ovine UCP1 is a potential gene marker for carcass traits. | |
dc.format.extent | pp.437-444 | |
dc.format.medium | Print-Electronic | |
dc.identifier | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=elements_prod&SrcAuth=WosAPI&KeyUT=WOS:000345272600004&DestLinkType=FullRecord&DestApp=WOS_CPL | |
dc.identifier.citation | Yang, G., Forrest, R., Zhou, H., Hodge, S.,& Hickford, J. (2014). Genetic variation in the ovine uncoupling protein 1 gene: association with carcass traits in New Zealand (NZ) Romney sheep, but no association with growth traits in either NZ Romney or NZ Suffolk sheep. Journal of Animal Breeding and Genetics, 131, 437-444. doi:10.1111/jbg.12097 | |
dc.identifier.doi | 10.1111/jbg.12097 | |
dc.identifier.eissn | 1439-0388 | |
dc.identifier.issn | 0931-2668 | |
dc.identifier.other | 24909360 (pubmed) | |
dc.identifier.uri | https://hdl.handle.net/10182/7941 | |
dc.language | en | |
dc.language.iso | en | |
dc.publisher | Wiley | |
dc.relation | The original publication is available from Wiley - https://doi.org/10.1111/jbg.12097 - http://onlinelibrary.wiley.com/doi/10.1111/jbg.12097/epdf | |
dc.relation.isPartOf | Journal of Animal Breeding and Genetics | |
dc.relation.uri | https://doi.org/10.1111/jbg.12097 | |
dc.rights | © 2014 Blackwell Verlag GmbH | |
dc.subject | carcass composition | |
dc.subject | growth rate | |
dc.subject | NZ Romney sheep | |
dc.subject | NZ Suffolk sheep | |
dc.subject | PCR-SSCP | |
dc.subject | uncoupling protein 1 | |
dc.subject.anzsrc2020 | ANZSRC::3003 Animal production | |
dc.subject.anzsrc2020 | ANZSRC::3102 Bioinformatics and computational biology | |
dc.subject.mesh | Animals | |
dc.subject.mesh | Sheep | |
dc.subject.mesh | Ion Channels | |
dc.subject.mesh | Mitochondrial Proteins | |
dc.subject.mesh | Genetic Markers | |
dc.subject.mesh | Body Composition | |
dc.subject.mesh | Molecular Sequence Data | |
dc.subject.mesh | New Zealand | |
dc.subject.mesh | Body Fat Distribution | |
dc.subject.mesh | Genetic Variation | |
dc.subject.mesh | Uncoupling Protein 1 | |
dc.title | Genetic variation in the ovine uncoupling protein 1 gene: Association with carcass traits in New Zealand (NZ) Romney sheep, but no association with growth traits in either NZ Romney or NZ Suffolk sheep | |
dc.type | Journal Article | |
lu.contributor.unit | LU | |
lu.contributor.unit | LU|Agriculture and Life Sciences | |
lu.contributor.unit | LU|Agriculture and Life Sciences|AGSC | |
lu.contributor.unit | LU|Research Management Office | |
lu.contributor.unit | LU|Research Management Office|OLD QE18 | |
lu.contributor.unit | LU|Centre of Excellence for One Biosecurity Research, Analysis and Synthesis | |
lu.identifier.orcid | 0000-0001-7620-3160 | |
lu.identifier.orcid | 0000-0001-9313-761X | |
pubs.issue | 6 | |
pubs.notes | Accepted 30 Apr 2014 | |
pubs.publication-status | Published | |
pubs.publisher-url | http://onlinelibrary.wiley.com/doi/10.1111/jbg.12097/epdf | |
pubs.volume | 131 |